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Patients who took ginger 1 g appeared to experience less nausea incidence, especially within hours of the procedure, and some reported less vomiting also Pongrojpaw and Chiamchanya This idea was supported by the results of a randomized, double-blind trial in which healthy volunteers reported that ginger effectively accelerated gastric emptying and stimulated antral contractions Wu et al. Enhanced maze performance and reduced oxidative stress by combined extracts of zingiber officinale and ginkgo biloba in the aged rat. Chemopreventive efficacy of ginger, a naturally occurring anticarcinogen during the initiation, post-initiation stages of 1,2 dimethylhydrazine-induced colon cancer. Ginger has been recommended to combat nausea associated with chemotherapy Sharma and Gupta ; Grant and Lutz Effect of [6]-gingerol on pro-inflammatory cytokine production and costimulatory molecule expression in murine peritoneal macrophages.

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However, in the last few years, more organized scientific investigations have focused on the mechanisms and targets of ginger and its various components.

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Ginger ingredients reduce viability of gastric cancer cells via distinct mechanisms. At least one group found that administration or consumption of standardized ginger extract decreased aortic atherosclerotic lesion areas, plasma triglycerides and cholesterol, low-density lipoprotein LDL -associated lipid peroxides, and LDL aggregation in mice Fuhrman et al. Gingerols are the major constituents of fresh ginger and are found slightly reduced in dry ginger, whereas the concentrations of shogaols, which are the major gingerol dehydration products, are more abundant Jolad et al. Ginger root is commonly recommended for preventing seasickness Schmid et al.

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